Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) classified as a selective growth hormone secretagogue and ghrelin receptor (GHS-R1a) agonist. Its high selectivity for growth hormone release, with minimal reported activity at receptors governing cortisol, prolactin, and ACTH secretion, has made it a widely used tool compound in endocrinology research focused on isolating GH-axis signaling from broader neuroendocrine responses.

Published studies have characterized the binding affinity and efficacy of Ipamorelin at the GHS-R1a receptor, its pulsatile effects on growth hormone secretion in animal models, and its use as a comparator compound in structure-activity relationship studies of growth hormone secretagogues. Additional research has examined downstream effects on IGF-1 expression and metabolic parameters in preclinical models.

Ares Research supplies Ipamorelin as a research-grade lyophilized powder with documented purity and identity. This product is provided exclusively for in vitro laboratory research and is not approved for human or veterinary use.