Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) classified as a selective growth hormone secretagogue and ghrelin receptor (GHS-R1a) agonist. Its high selectivity for growth hormone release, with minimal reported activity at receptors governing cortisol, prolactin, and ACTH secretion, has made it a widely used tool compound in endocrinology research focused on isolating GH-axis signaling from broader neuroendocrine responses.
Published studies have characterized the binding affinity and efficacy of Ipamorelin at the GHS-R1a receptor, its pulsatile effects on growth hormone secretion in animal models, and its use as a comparator compound in structure-activity relationship studies of growth hormone secretagogues. Additional research has examined downstream effects on IGF-1 expression and metabolic parameters in preclinical models.
Ares Research supplies Ipamorelin as a research-grade lyophilized powder with documented purity and identity. This product is provided exclusively for in vitro laboratory research and is not approved for human or veterinary use.
Research References
The following references are provided for informational purposes. This product is for laboratory research use only by qualified professionals.
